Drugs | Possible Mechanisms | %SCD reduction |
---|---|---|
Beta Blockers | decrease sympathetic tone, stabilize myocardium | 44% in CIBIS-II |
Aldosterone Antagonist | reduce inflammation | 29% in RALES |
ACEI/ARB | reduce electrical irritability | 20% in Meta-analysis |
Statin | stabilize plaques | 40% in AVID |
Amiodarone | - | similar events with placebo in SCD-HeFT |